Republican South Carolina Senate candidate Darline Graham is projected to have lost her race, handing Democrats their first victory in the state for 28 years.
Democrat Annie Andrews, a former paediatrician, was on course to pull off a stunning upset
Graham was appointed to fill the seat in July after the sudden death of her brother, Senator Lindsey Graham, a move that won support from President Donald Trump.
A political newcomer, she conceded during the primary that she was “not that informed on national security”.